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Abstract

Malaria is an infectious disease that remains a global health concern, particularly in Asia and Africa. The success of malaria medication largely depends on patients' adherence to the prescribed therapeutic regimen. This article aims to identify the level of adherence to malaria treatment and the factors that influence it, based on observational studies. A narrative review was conducted using the PRISMA approach, involving 12 articles published between 2019 - 2023 from various countries. The results indicate that adherence levels vary widely, ranging from 15.6% to 93.31%, depending on respondent characteristics and the intervention strategies implemented. Factors influencing adherence include patient-related factors (perceived wellness, gender, age, education, place of residence, religion, medication storage habits, DOT supporters, forgetfulness, and knowledge of malaria treatment), therapy-related factors (type of antimalarial drug, drug characteristics, treatment duration), condition-related factors (vomiting, history of malaria), health system factors (type of health facility, drug availability, treatment education methods), and socioeconomic factors. These findings underscore the importance of a multidimensional approach to improving malaria treatment adherence as part of global malaria elimination efforts.

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